Genetic variations associated with pharmacoresistant epilepsy (Review)
نویسندگان
چکیده
منابع مشابه
Genetic variations and associated pathophysiology in the management of epilepsy
The genomic era has enabled the application of molecular tools to the solution of many of the genetic epilepsies, with and without comorbidities. Massively parallel sequencing has recently reinvigorated gene discovery for the monogenic epilepsies. Recurrent and novel copy number variants have given much-needed impetus to the advancement of our understanding of epilepsies with complex inheritanc...
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CONTEXT Patients with pharmacoresistant epilepsy have increased mortality compared with the general population, but patients with pharmacoresistant temporal lobe epilepsy who meet criteria for surgery and who become seizure-free after anterior temporal lobe resection have reduced excess mortality vs those with persistent seizures. OBJECTIVE To quantify the potential survival benefit of anteri...
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not available S230 Neurosciences 2003; Vol. 8 Supplement 2 Indications for invasive recording and role of intraoperative monitoring and mapping in epilepsy Yousef G. Comair Division of `neurosurgery, American University of Beirut, Lebanon Abstract not availablenot available Neurosciences 2003; Vol. 8 Supplement 2 S231
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Functional magnetic resonance imaging (fMRI) triggered by scalp electroencephalography (EEG) recordings has become a promising new tool for noninvasive epileptic focus localization. Studies to date have shown that it can be used safely and that highly localized information can be obtained. So far, no reports using comprehensive clinical information and/or long-term follow-up after epilepsy surg...
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transport GSH adducts, which overstates the case, otherwise standard CF therapies would be toxic to CF persons. For example, MRP channels have been identified at the basolateral side of human lung epithelial cells, which channels function even in CF. (4) According to the most recent peer-reviewed literature, the primary selection force for CF mutation was the bubonic plague epidemic of the 1300...
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2020
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2020.10999